产品货号:
Z19668
中文名称:
KIF15抗体
英文名称:
Anti-KIF15 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-KIF15 Antibody |
指标别名 | HKLP2,KIF15,kinesin family member 15,Kinesin like protein 2,Kinesin like protein 7,Kinesin like protein KIF15,KLP2,KNSL7,NY BR 62 |
克隆性 | Polyclonal |
检验物种 | human,rat |
应用范围 | IHC,WB,ICC/IF,FCM,ELISA |
基因名称 | KIF15 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived human KIF15 recombinant protein (Position:M1201-S1388). |
实际分子量 | 150~160KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Kinesin family member 15 is a protein that in humans is encoded by the KIF15 gene.It is mapped to 3p21.31.This gene encodes a motor protein that is part of the kinesin superfamily.KIF15 maintains half spindle separation by opposing forces generated by other motor proteins.KIF15 co-localizes with microtubules and actin filaments in both dividing cells and in postmitotic neurons.KIF15 (also known as Kinesin-12 and HKLP2) is a motor protein expressed in all cells during mitosis and in postmitotic neurons undergoing axon growth.KIF15 maintains bipolar microtubule spindle apparatus in dividing cells and shares redundant functions with KIF11.KIF15 is thought to promote spindle assembly by cross-linking and sliding along microtubules creating a separation between centrosomes.HeLa cells depleted of KIF11,with reduced microtubule dynamics,are able to form bipolar spindles from acentrosomal asters in a KIF15 dependent manner.Hence,inhibition of KIF15 function will be a vital therapeutic approach in cancer chemotherapy. |
Uniprot ID | Q9NS87 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
推荐稀释比 | Western blot (WB) 1:500~2000 Immunohistochemistry (IHC) 1:50~400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50~400 Flow cytometry (FCM) 1~3μg/1×106 cells Enzyme linked immunosorbent assay (ELISA) 1:100~1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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